Barbara Romain earned a BFA degree from the Philadelphia College of Art (now University of the Arts) and an MFA degree from Otis College of Art and Design in Los Angeles. Her award-winning paintings are widely exhibited and she is the recipient of multiple-year Artist in Residence awards from the City of Los Angeles Department of Cultural Affairs and the California Arts Council. She is a Teaching Artist Fellow for VSA Arts, an affiliate of the John F. Kennedy Center for the Art in Washington, D.C.
In 1992, she co-founded Art Options, an arts education program which served hundreds of Los Angeles inner-city teenagers through 2007. Currently she is a Professor at Columbia College Hollywood, School of Film & Television in Tarzana, CA.
Diagnosed with a rare form of retinitis pigmentosa in 1984, she is legally blind.
A few of the venues where her paintings have been shown include the Philadelphia Museum of Art, the San Diego Art Institute, the San Francisco Art Commission Gallery, the Fort Collins Museum of Art, the Los Angeles Municipal Gallery, the Holter Museum in Helena Mt, and the Terrace Gallery of the John F. Kennedy Center in Washington, D.C.,
In June 2013, her work was featured in ART BLIND, an international exhibit of artists with Visual Impairment in Cologne, Germany.